News and Events
Recent News
Woburn Massachusetts, Mon, 1 Mar 2010
Kapa Biosystems and the Broad Institute release a joint poster presentation at the Advances in Genome Biology and Technology conference in Marco Island, Florida. The poster describes the implementation of the new KAPA Library Quantification Kits into the high-throughput Illumina GA pipeline at the Broad Institute. The result was streamlined workflows, reduced cluster density variability, and the ability to quantify low concentration libraries.
Download the AGBT 2010 poster here>>
More information on the new KAPA Library Quantification Kits here>>
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Woburn Massachusetts, Tue, 12 Jan 2010
WOBURN, Mass. - Kapa Biosystems and VWR International, LLC announced today that they have entered into a non-exclusive North American distribution agreement for Kapa Biosystems' line of next-generation PCR reagents. Kapa Biosystems employs a high-throughput molecular evolution technology platform to engineer DNA-modifying enzymes for applications in DNA amplification, next-generation sequencing, and molecular diagnostics. Under the terms of the agreement, VWR has the rights to distribute Kapa Biosystems' portfolio of innovative products for applications such as high fidelity PCR, fast PCR, long range PCR, whole blood PCR, crude sample PCR, and single protocol PCR. VWR, a global laboratory supply and distribution company with worldwide sales in excess of $3.7 billion in 2008, enables the advancement of the world’s most critical research through the distribution of a highly diversified product line to most of the top pharmaceutical and biotech companies, as well as industrial, educational and governmental organizations.
"Kapa Biosystems' high performance PCR reagents allow researchers to consolidate protocols, simplify workflows, save time, and achieve results not possible with reagents based on wild-type enzymes," said Ron McEwan, CEO of Kapa Biosystems. "Kapa's agreement with VWR will significantly expand our ability to offer the benefits of these novel products to the broader life sciences research community."
The DNA polymerases contained in Kapa Biosystems' reagents have been engineered through a process of molecular evolution and possess unique amino acid modifications that confer dramatic improvements to the function of the enzymes. Examples of optimized polymerases include: KAPA2G FAST DNA Polymerase - capable of synthesizing DNA in 50% less time with high sensitivity; KAPA2G ROBUST DNA Polymerase - more processive and tolerant of common PCR inhibitors carried over from DNA extraction; KAPA HiFi DNA Polymerase - strong proofreading capability resulting in the highest fidelity of any polymerase for PCR; and KAPA Blood DNA Polymerase - capable of amplifying DNA direct from whole blood without the need for extraction.
For more information on Kapa Biosystems' portfolio of next-generation PCR reagents visit:http://www.kapabiosystems.com/products
About Kapa Biosystems
Kapa Biosystems is a next-generation life science reagents supplier that employs high-throughput molecular evolution to optimize enzymes for DNA amplification, next-generation DNA sequencing and molecular diagnostic applications. Kapa Biosystems offers a range of next-generation PCR reagents that are fundamentally different at the protein level and designed specifically for PCR. The company is based in Woburn, Massachusetts with an ISO 9001:2008 certified research and development facility in Cape Town, South Africa. For more information about Kapa Biosystems, please visit the company’s website at www.kapabiosystems.com.
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Woburn Massachusetts, Wed, 28 Oct 2009
October 27th, 2009
Woburn, MA – Life science reagents supplier Kapa Biosystems announced today that its Research, Development and Manufacturing facility has received ISO 9001:2008 certification from SABS Commercial (Pty) Ltd. The Woburn, Mass.-based firm employs a high-throughput molecular evolution technology platform to optimize enzymes for DNA amplification, next-generation DNA sequencing and molecular diagnostic applications. Kapa Biosystems offers a range of PCR reagents that contain novel DNA polymerases that are fundamentally different at the protein level when compared to wild-type enzymes.
The ISO 9000 family of standards represents an international consensus on good quality management practices. ISO 9001:2008 provides a set of standardized requirements for a quality management system and is the only standard in the family against which organizations can be certified. The ISO 9001:2008 standard provides a tried and tested framework for taking a systematic approach to managing the organization's processes so that they consistently turn out product that satisfies customers' expectations, said Kapa Biosystems.
About Kapa Biosystems
Kapa Biosystems is a next-generation life science reagents supplier that employs high-throughput molecular evolution to optimize enzymes for DNA amplification, next-generation sequencing and molecular diagnostic applications. The company is based in Woburn, Massachusetts with a research and development facility in Cape Town, South Africa. For more information about Kapa Biosystems, please visit the company’s website at www.kapabiosystems.com.
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Woburn Massachusetts, Mon, 26 Oct 2009
High-throughput qPCR is a demanding application that requires consistent and reproducible results from low-volume, high-speed assays. The combination of the Eppendorf Mastercycler® ep realplex4 S real-time PCR instrument and KAPA SYBR® FAST and KAPA PROBE FAST qPCR Kits from Kapa Biosystems provides an industry-leading solution for high-performance, fast qPCR without compromising reaction efficiency and reproducibility.
For more information on the use of KAPA SYBR® FAST for high-throughput fast qPCR please download the joint application note with Eppendorf North America here>>
For more information on the use of KAPA PROBE FAST for high-throughput fast qPCR please download the joint application note with Eppendorf North America here>>
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Woburn Massachusetts, Mon, 26 Oct 2009
Consistent amplification of a broad range of targets, covering the full spectrum of AT- and GC-rich content, using a single set of reaction conditions and one cycling protocol is the ultimate goal of any lab performing routine PCR. This concept of "Single Protocol PCR" has proven impractical due to the inherent limitations of wild-type Taq DNA Polymerase – most notably its inefficient amplification of challenging templates and narrow range of optimal PCR conditions. In order to improve PCR success rates and minimize reaction failures, many laboratories are forced to segregate difficult targets from "easy" targets and optimize individual reactions. The resulting subset of specialized assays disrupts workflows and increases turnaround time and cost by requiring a myriad of PCR reagents, reaction conditions and cycling protocols.
KAPA2G Robust HoStart ReadyMix contains a novel, second-generation (2G) enzyme engineered for higher processivity and improved tolerance to common PCR inhibitors through a process of molecular evolution. The unique features of the enzyme supports versatile and robust amplification of a wide range of template and amplicon types. Combined with a proprietary reaction buffer that facilitates primer annealing, successful amplification of both AT- and GC-rich amplicons can finally be achieved using a simplified reaction setup and a single, fast cycling protocol that typically requires 20 – 50% less cycling time than protocols designed for wild-type DNA polymerases.
For more detailed protocol information on consolidating PCR protocols download the Single Protocol PCR Application Note here>>
Ordering and product information for KAPA2G Robust HotStart ReadyMix here>>
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